How Does Grapefruit Extract Work?

According to studies, the mode of action of the principal active ingredient of GSE – Grapefruit Extract shows itself in the cytoplasmic membrane of target micro-organisms.

The active ingredients of the extract disorganize the cytoplasmic membrane, thereby preventing the uptake of amino acids.

At the same time, there is a leakage of the low molecular weight cellular contents through the cytoplasmic membrane.

As a result the pathogen is then inactivated. The time for this is generally shorter than that of most comparable preparations.

Grapefruit Extract does not allow bacteria to build up a resistance. To date there is no evidence that any type of micro-organism has ever built up a resistance to the active ingredients of Grapefruit Extract.

Due to the mode of its activity it is believed that this resistance is impossible as Grapefruit Extract completely disrupts the cytoplasmic membrane of the organisms.

What is not known is how Grapefruit Extract can affect the cell membranes of such a diverse group of microbes with virtually no toxicity toward animal life?

An “Acute Oral Toxicity Study” which was carried out many years ago by an independent laboratory concluded that you would have to take 4,000 times the normal recommended adult internal dose to have even a 50% chance of poisoning.

GSE Applications

Here are just some of the external / topical uses of Grapefruit

Extract including, but not limited to:

  • Mouth and Lips: mouthwash, mouth ulcers, thrush, bad
    breath, cracked lips, sunburned lips, and cold sores


  • Teeth and Gums: plaque, tooth decay, toothaches, tooth
    extraction, gingivitis, and toothbrush cleaner


  • Nose and Sinuses: sinusitis, runny nose (rhinitis), and
    nasal ulcers


  • Throat: sore throat, tonsillitis, coughs, hoarseness, and


  • Ears: ear cleaning, earaches, and inflammation of the
    middle ear (otitis media) in conjunction with internal use


  • Face: acne and shaving


  • Scalp and Hair: shampoo, dandruff, itching scalp, and head


  • Skin: small cuts, skin abrasions, scratches, minor burns,
    rashes, dermatitis, psoriasis, shingles, eczema, nettle rash, insect bites and
    stings, tick and leech bites, leg ulcers, warts, and skin fungi


  • Feet: Athlete’s foot, sweaty feet, callouses, corns,
    blisters, nail fungi, and cuticle infections


  • Vagina and genitals: vaginitis, yeast infections, vaginal
    parasites, feminine hygiene, and fungal and parasitic diseases.


Examples of internal uses include:


  • Acute and chronic inflammations in general


  • Colds and Flu


  • Gastrointestinal infections


  • Gastritis and gastric and duodenal ulcers


  • Candida albicans and other fungal


  • Parasitic diseases


  • Allergies

Main Grapefruit use

In a good year, a single Grapefruit tree can produce around 600 kilos of fruit.

Down in sunny Florida they say that from 1 acre of a grove it is possible to harvest 400-700 boxes of grapefruit. 700 boxes of grapefruit weigh approximately 27.5 tons (circa 60,000 pounds).

Setting aside the fruit used in the manufacture of Grapefruit Extract, around 40% of the Grapefruit harvested each season is used for juice. The other 60% is sold as fresh grapefruit.